CMap Candidate Details

Structure:
CMap ID: C17326
Pert ID: BRD-K46742498
Compound Name: alosetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: Cc1[nH]cnc1CN1CCc2c(C1=O)c1ccccc1n2C
InchiKey: JSWZEAMFRNKZNL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24443 BRD-K46742498 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24582 BRD-K46742498 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24779 BRD-K46742498 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24911 BRD-K46742498 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25026 BRD-K46742498 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25163 BRD-K46742498 PC3 10 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
25374 BRD-K46742498 VCAP 10 uM 24 h 0.17 0.72 0.0 -0.33 -1.12 0.93
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).