CMap Candidate Details

Structure:
CMap ID: C17332
Pert ID: BRD-K46766488
Compound Name: S-14506
Targets: HTR1A
MoA: Serotonin receptor agonist
SMILES: COc1ccc2cccc(N3CCN(CCNC(=O)c4ccc(F)cc4)CC3)c2c1
InchiKey: IFMQODYDAUKKEN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6757 BRD-K46766488 A375 10 uM 24 h 0.28 1.15 0.32 0.0 0.0 0.0
7158 BRD-K46766488 A549 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.42
7326 BRD-K46766488 HA1E 10 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
8001 BRD-K46766488 HT29 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.18
8190 BRD-K46766488 MCF??7.00 10 uM 6 h 0.24 0.99 0.1 0.0 0.0 0.0
8374 BRD-K46766488 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
8682 BRD-K46766488 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
99571 BRD-K46766488 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).