CMap Candidate Details

Structure:
CMap ID: C01735
Pert ID: BRD-A71203467
Compound Name: L-stepholidine
Targets: DRD1; DRD2
MoA: Dopamine receptor agonist; Dopamine receptor antagonist
SMILES: COc1cc2CCN3Cc4c(OC)c(O)ccc4CC3c2cc1O
InchiKey: JKPISQIIWUONPB-UHFFFAOYSA-N
Compound Aliases: l-stepholidine

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6852 BRD-A71203467 A375 10 uM 6 h -0.18 -0.73 0.0 0.0 0.0 0.0
7107 BRD-A71203467 A549 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
7259 BRD-A71203467 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7584 BRD-A71203467 HCC515 10 uM 6 h 0.19 0.79 0.0 0.0 0.0 0.0
7801 BRD-A71203467 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8061 BRD-A71203467 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
8467 BRD-A71203467 PC3 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.3
8775 BRD-A71203467 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).