CMap Candidate Details

Structure:
CMap ID: C01736
Pert ID: BRD-A71262238
Compound Name: nafadotride
Targets: DRD3
MoA: Dopamine receptor antagonist
SMILES: CCCCN1CCCC1CNC(=O)c1cc(C#N)c2ccccc2c1OC
InchiKey: IDZASIQMRGPBCQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1707 BRD-A71262238 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1843 BRD-A71262238 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2202 BRD-A71262238 PC3 10 uM 24 h -0.18 -0.74 0.0 -0.27 -0.89 0.27
2502 BRD-A71262238 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21840 BRD-A71262238 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22940 BRD-A71262238 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41889 BRD-A71262238 A549 10 uM 24 h 0.0 0.0 0.0 0.26 0.9 0.23
42231 BRD-A71262238 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42877 BRD-A71262238 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43136 BRD-A71262238 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43429 BRD-A71262238 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43739 BRD-A71262238 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44025 BRD-A71262238 SKB 10 uM 24 h 0.19 0.79 0.0 0.32 1.14 0.85
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).