CMap Candidate Details

Structure:
CMap ID: C17360
Pert ID: BRD-K46862739
Compound Name: metyrapone
Targets: CYP11B1
MoA: Cytochrome P450 inhibitor
SMILES: CC(C)(C(=O)c1cccnc1)c1cccnc1
InchiKey: FJLBFSROUSIWMA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6758 BRD-K46862739 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7159 BRD-K46862739 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7327 BRD-K46862739 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7664 BRD-K46862739 HCC515 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
8002 BRD-K46862739 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8128 BRD-K46862739 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8683 BRD-K46862739 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
52299 BRD-K46862739 PC3 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
99572 BRD-K46862739 U2OS 8 uM 6 h -0.21 -0.86 0.02 -0.26 -0.88 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).