CMap Candidate Details

Structure:
CMap ID: C17388
Pert ID: BRD-K46970505
Compound Name: cefozopran
Targets: --
MoA: --
SMILES: CON=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccn4ncccc34)=C(N2C1=O)C(O)=O)c1nsc(N)n1
InchiKey: QDUIJCOKQCCXQY-WHJQOFBOSA-O
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125591 BRD-K46970505 A375 0.37 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
125619 BRD-K46970505 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125657 BRD-K46970505 HEK293 0.125 uM 24 h 0.22 0.92 0.04 -0.3 -1.01 0.58
125744 BRD-K46970505 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125805 BRD-K46970505 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125942 BRD-K46970505 YAPC 3.33 uM 24 h -0.25 -1.05 0.24 0.0 0.0 0.0
133706 BRD-K46970505 HA1E 0.74 uM 24 h -0.3 -1.24 0.67 0.0 0.0 0.0
133774 BRD-K46970505 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
133804 BRD-K46970505 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
133829 BRD-K46970505 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.12
133889 BRD-K46970505 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133920 BRD-K46970505 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.08
133950 BRD-K46970505 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133984 BRD-K46970505 THP1 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).