CMap Candidate Details

Structure:
CMap ID: C01739
Pert ID: BRD-A71390734
Compound Name: idarubicin
Targets: TOP2A
MoA: Topoisomerase inhibitor
SMILES: CC1OC(CC(N)C1O)O[C@H]1C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O
InchiKey: XDXDZDZNSLXDNA-YMYDAGKFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1304 BRD-A71390734 MCF??7.00 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1390 BRD-A71390734 U2OS 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9055 BRD-A71390734 A375 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9306 BRD-A71390734 AGS 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9610 BRD-A71390734 H1299 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9972 BRD-A71390734 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10340 BRD-A71390734 HCC515 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10415 BRD-A71390734 HCT116 0.08 uM 6 h 0.0 0.0 0.0 0.4 1.42 2.2
10686 BRD-A71390734 HEPG2 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10916 BRD-A71390734 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11360 BRD-A71390734 NCIH2073 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11667 BRD-A71390734 NCIH508 0.08 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.64
11932 BRD-A71390734 NCIH596 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12220 BRD-A71390734 NOMO1 0.08 uM 6 h 0.26 1.09 0.22 -0.35 -1.17 1.12
12547 BRD-A71390734 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
13076 BRD-A71390734 THP1 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13162 BRD-A71390734 U937 0.08 uM 6 h 0.26 1.08 0.2 -0.28 -0.95 0.41
13429 BRD-A71390734 VCAP 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90564 BRD-A71390734 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).