CMap Candidate Details

Structure:
CMap ID: C01740
Pert ID: BRD-A71459254
Compound Name: cymarin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: COC1CC(O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)C(CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)OC(C)C1O
InchiKey: XQCGNURMLWFQJR-LZLVDNNYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2818 BRD-A71459254 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
3117 BRD-A71459254 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3588 BRD-A71459254 PC3 10 uM 6 h 0.0 0.0 0.0 -0.52 -1.74 15.65
3930 BRD-A71459254 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44259 BRD-A71459254 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44490 BRD-A71459254 A549 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.63 15.65
44784 BRD-A71459254 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45104 BRD-A71459254 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45376 BRD-A71459254 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45749 BRD-A71459254 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45904 BRD-A71459254 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46220 BRD-A71459254 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46535 BRD-A71459254 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).