CMap Candidate Details

Structure:
CMap ID: C17405
Pert ID: BRD-K47029922
Compound Name: tranylcypromine
Targets: KDM1A; MAOA; MAOB
MoA: Monoamine oxidase inhibitor
SMILES: N[C@@H]1C[C@H]1c1ccccc1
InchiKey: AELCINSCMGFISI-DTWKUNHWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93627 BRD-K47029922 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93669 BRD-K47029922 ASC 1.11 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.01
93734 BRD-K47029922 CD34 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
93769 BRD-K47029922 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93808 BRD-K47029922 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93859 BRD-K47029922 HEK293 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93900 BRD-K47029922 HELA 10 uM 24 h -0.22 -0.93 0.07 -0.26 -0.86 0.22
93941 BRD-K47029922 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93971 BRD-K47029922 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
94043 BRD-K47029922 JURKAT 0.12 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.73
94072 BRD-K47029922 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94181 BRD-K47029922 NPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94202 BRD-K47029922 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94258 BRD-K47029922 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94309 BRD-K47029922 SKL 10 uM 24 h 0.25 1.05 0.17 -0.25 -0.86 0.2
94353 BRD-K47029922 THP1 10 uM 24 h -0.3 -1.26 0.71 0.0 0.0 0.0
94391 BRD-K47029922 YAPC 0.04 uM 24 h -0.32 -1.32 0.83 -0.24 -0.82 0.15
98388 BRD-K47029922 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).