CMap Candidate Details

Structure:
CMap ID: C17428
Pert ID: BRD-K47095176
Compound Name: talnetant
Targets: TACR3
MoA: Tachykinin antagonist
SMILES: CC[C@H](NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1
InchiKey: BIAVGWDGIJKWRM-FQEVSTJZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125237 BRD-K47095176 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125257 BRD-K47095176 A549 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
125308 BRD-K47095176 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125373 BRD-K47095176 HT29 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
125395 BRD-K47095176 JURKAT 0.04 uM 24 h -0.22 -0.92 0.06 -0.31 -1.03 0.65
125442 BRD-K47095176 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125493 BRD-K47095176 PC3 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.76 0.07
133387 BRD-K47095176 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133417 BRD-K47095176 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133514 BRD-K47095176 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
133551 BRD-K47095176 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133604 BRD-K47095176 THP1 2.22 uM 24 h 0.27 1.15 0.32 0.0 0.0 0.0
133628 BRD-K47095176 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).