CMap Candidate Details

Structure:
CMap ID: C01748
Pert ID: BRD-A71765365
Compound Name: mepireserpate
Targets: SLC18A1; SLC18A2
MoA: Catecholamine depleting sympatholytic
SMILES: COC1C(CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6
InchiKey: QEVHRUUCFGRFIF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6684 BRD-A71765365 A375 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
6953 BRD-A71765365 A549 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
7260 BRD-A71765365 HA1E 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
7585 BRD-A71765365 HCC515 10 uM 6 h -0.18 -0.75 0.0 -0.18 -0.6 0.0
7967 BRD-A71765365 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8232 BRD-A71765365 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8468 BRD-A71765365 PC3 10 uM 6 h 0.0 0.0 0.0 0.41 1.43 2.21
8616 BRD-A71765365 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).