CMap Candidate Details

Structure:
CMap ID: C17494
Pert ID: BRD-K47323024
Compound Name: methapyrilene
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN(C)CCN(Cc1cccs1)c1ccccn1
InchiKey: HNJJXZKZRAWDPF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49848 BRD-K47323024 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50367 BRD-K47323024 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50540 BRD-K47323024 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50754 BRD-K47323024 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.07
51034 BRD-K47323024 VCAP 10 uM 24 h 0.26 1.1 0.24 -0.21 -0.72 0.04
52407 BRD-K47323024 HA1E 20 uM 6 h 0.19 0.78 0.0 0.33 1.17 0.97
52488 BRD-K47323024 PC3 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52676 BRD-K47323024 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52805 BRD-K47323024 HEPG2 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99576 BRD-K47323024 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).