CMap Candidate Details

Structure:
CMap ID: C17533
Pert ID: BRD-K47448802
Compound Name: BRD-K47448802
Targets: CHRM1
MoA: Acetylcholine receptor agonist
SMILES: CCOC(=O)N1CCC(CC1)NCCNC(=O)c2ccccc2
InchiKey: VNRSRVXFGIQMBW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21869 BRD-K47448802 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22135 BRD-K47448802 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
22778 BRD-K47448802 HCC515 10 uM 6 h -0.21 -0.89 0.03 0.21 0.75 0.04
23069 BRD-K47448802 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23367 BRD-K47448802 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23586 BRD-K47448802 MCF??7.00 10 uM 24 h -0.19 -0.78 0.0 -0.33 -1.13 0.97
23864 BRD-K47448802 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24319 BRD-K47448802 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
115107 BRD-K47448802 U2OS 20 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.62
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).