CMap Candidate Details

Structure:
CMap ID: C01760
Pert ID: BRD-A72066420
Compound Name: mifobate
Targets: PPARG
MoA: PPAR receptor antagonist
SMILES: COP(=O)(OC)OC(c1ccc(Cl)cc1)P(=O)(OC)OC
InchiKey: VQHUQHAPWMNBLP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6686 BRD-A72066420 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7109 BRD-A72066420 A549 10 uM 6 h 0.24 1.0 0.11 0.0 0.0 0.0
7968 BRD-A72066420 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8777 BRD-A72066420 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100309 BRD-A72066420 U2OS 10 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.84
126678 BRD-A72066420 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126727 BRD-A72066420 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126814 BRD-A72066420 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126857 BRD-A72066420 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126901 BRD-A72066420 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126970 BRD-A72066420 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134778 BRD-A72066420 HEK293 0.03 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
134884 BRD-A72066420 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134909 BRD-A72066420 JURKAT 0.08 uM 24 h -0.22 -0.9 0.04 -0.26 -0.86 0.21
134973 BRD-A72066420 PC3 0.08 uM 24 h 0.22 0.9 0.03 -0.31 -1.03 0.63
135001 BRD-A72066420 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).