CMap Candidate Details

Structure:
CMap ID: C17616
Pert ID: BRD-K47659338
Compound Name: EMD-386088
Targets: HTR6
MoA: Serotonin receptor agonist
SMILES: Cc1[nH]c2ccc(Cl)cc2c1C1=CCNCC1
InchiKey: BPPGPYJBCVXILI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5210 BRD-K47659338 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5337 BRD-K47659338 HA1E 10 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
5642 BRD-K47659338 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6282 BRD-K47659338 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6560 BRD-K47659338 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37292 BRD-K47659338 A549 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.97
37675 BRD-K47659338 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
37911 BRD-K47659338 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38091 BRD-K47659338 HT29 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.37
38236 BRD-K47659338 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38499 BRD-K47659338 NPC 10 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
38736 BRD-K47659338 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99581 BRD-K47659338 U2OS 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).