CMap Candidate Details

Structure:
CMap ID: C17622
Pert ID: BRD-K47679368
Compound Name: bromfenac
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: Nc1c(CC(O)=O)cccc1C(=O)c1ccc(Br)cc1
InchiKey: ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49849 BRD-K47679368 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50015 BRD-K47679368 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50192 BRD-K47679368 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50368 BRD-K47679368 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50541 BRD-K47679368 HT29 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.76 0.07
50755 BRD-K47679368 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50845 BRD-K47679368 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51154 BRD-K47679368 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).