CMap Candidate Details

Structure:
CMap ID: C17641
Pert ID: BRD-K47717570
Compound Name: NBQX
Targets: GRIA1
MoA: Glutamate receptor antagonist
SMILES: NS(=O)(=O)c1cccc2c3nc(O)c(O)nc3cc([N+](=O)[O-])c12
InchiKey: UQNAFPHGVPVTAL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5458 BRD-K47717570 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5781 BRD-K47717570 HCC515 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
6030 BRD-K47717570 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6101 BRD-K47717570 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6196 BRD-K47717570 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
6429 BRD-K47717570 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37166 BRD-K47717570 A375 10 uM 6 h 0.32 1.35 0.96 0.0 0.0 0.0
37392 BRD-K47717570 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37676 BRD-K47717570 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37912 BRD-K47717570 HEPG2 10 uM 6 h 0.23 0.98 0.09 0.0 0.0 0.0
38500 BRD-K47717570 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).