CMap Candidate Details
Structure:
CMap ID: | C00177 |
Pert ID: | BRD-A06916187 |
Compound Name: | CPI-613 |
Targets: | PDHA1 |
MoA: | Pyruvate dehydrogenase inhibitor |
SMILES: | OC(=O)CCCCC(CCSCc1ccccc1)SCc1ccccc1 |
InchiKey: | ZYRLHJIMTROTBO-UHFFFAOYSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
122548 | BRD-A06916187 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122579 | BRD-A06916187 | A549 | 0.125 uM | 24 h | 0.32 | 1.32 | 0.83 | 0.0 | 0.0 | 0.0 |
122602 | BRD-A06916187 | HA1E | 0.37 uM | 24 h | 0.21 | 0.88 | 0.01 | 0.25 | 0.88 | 0.19 |
122681 | BRD-A06916187 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.57 |
122724 | BRD-A06916187 | MCF10A | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.62 |
122795 | BRD-A06916187 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.16 |
122817 | BRD-A06916187 | YAPC | 1.11 uM | 24 h | 0.25 | 1.04 | 0.14 | -0.37 | -1.23 | 1.28 |
130937 | BRD-A06916187 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
130969 | BRD-A06916187 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
131046 | BRD-A06916187 | HUVEC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.11 |
131084 | BRD-A06916187 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.67 |
131121 | BRD-A06916187 | MDAMB231 | 0.03 uM | 24 h | 0.23 | 0.95 | 0.06 | 0.35 | 1.26 | 1.29 |