CMap Candidate Details

Structure:
CMap ID: C01773
Pert ID: BRD-A72483914
Compound Name: spiroxatrine
Targets: HTR1A
MoA: Serotonin receptor antagonist
SMILES: O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1
InchiKey: JVGBTTIJPBFLTE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6687 BRD-A72483914 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7110 BRD-A72483914 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7411 BRD-A72483914 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7969 BRD-A72483914 HT29 10 uM 6 h -0.27 -1.14 0.42 -0.25 -0.85 0.19
8137 BRD-A72483914 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8330 BRD-A72483914 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8778 BRD-A72483914 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91021 BRD-A72483914 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100310 BRD-A72483914 U2OS 10 uM 6 h 0.0 0.0 0.0 0.21 0.76 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).