CMap Candidate Details

Structure:
CMap ID: C17767
Pert ID: BRD-K48059230
Compound Name: YM-298198
Targets: GRM1
MoA: Glutamate receptor antagonist
SMILES: Cc1c(sc2nc3ccc(N)cc3n12)C(=O)NC1CCCCC1
InchiKey: VWOMTTIMBHBPBI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6760 BRD-K48059230 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7162 BRD-K48059230 A549 10 uM 6 h -0.26 -1.09 0.33 0.0 0.0 0.0
7329 BRD-K48059230 HA1E 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
7667 BRD-K48059230 HCC515 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
7873 BRD-K48059230 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8132 BRD-K48059230 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8376 BRD-K48059230 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8820 BRD-K48059230 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99587 BRD-K48059230 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).