CMap Candidate Details

Structure:
CMap ID: C17771
Pert ID: BRD-K48068743
Compound Name: teneligliptin
Targets: DPP4
MoA: Dipeptidyl peptidase inhibitor
SMILES: Cc1cc(N2CCN(CC2)[C@@H]2CN[C@@H](C2)C(=O)N2CCSC2)n(n1)-c1ccccc1
InchiKey: WGRQANOPCQRCME-PMACEKPBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95318 BRD-K48068743 A549 10 uM 48 h 0.0 0.0 0.0 -0.36 -1.2 1.16
95400 BRD-K48068743 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96357 BRD-K48068743 A375 3.33 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
125751 BRD-K48068743 HUVEC 1.11 uM 24 h 0.24 0.99 0.09 0.33 1.16 0.9
125786 BRD-K48068743 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125949 BRD-K48068743 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133712 BRD-K48068743 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133742 BRD-K48068743 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133777 BRD-K48068743 HELA 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
133808 BRD-K48068743 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
133867 BRD-K48068743 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
133893 BRD-K48068743 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133925 BRD-K48068743 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
133954 BRD-K48068743 PC3 2.22 uM 24 h -0.24 -1.02 0.17 0.0 0.0 0.0
133988 BRD-K48068743 THP1 0.08 uM 24 h 0.2 0.84 0.0 0.23 0.83 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).