CMap Candidate Details

Structure:
CMap ID: C01778
Pert ID: BRD-A72596465
Compound Name: GW-6471
Targets: PPARA
MoA: PPAR receptor antagonist
SMILES: CCOC(=O)NCC(Cc1ccc(OCCc2nc(oc2C)c3ccccc3)cc1)NC(=CC(=O)c4ccc(cc4)C(F)(F)F)C
InchiKey: UEPVEQWUZJXOKB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4177 BRD-A72596465 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4318 BRD-A72596465 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4625 BRD-A72596465 PC3 10 uM 24 h -0.21 -0.88 0.03 -0.23 -0.77 0.09
37099 BRD-A72596465 A375 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
37354 BRD-A72596465 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37543 BRD-A72596465 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37847 BRD-A72596465 HEPG2 10 uM 6 h 0.23 0.96 0.08 0.0 0.0 0.0
38036 BRD-A72596465 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38166 BRD-A72596465 MCF??7.00 10 uM 24 h -0.28 -1.16 0.45 0.0 0.0 0.0
38388 BRD-A72596465 NPC 10 uM 24 h 0.32 1.35 0.96 0.0 0.0 0.0
38658 BRD-A72596465 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
88083 BRD-A72596465 VCAP 30 uM 24 h 0.21 0.88 0.01 0.4 1.41 2.18
100311 BRD-A72596465 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).