CMap Candidate Details

Structure:
CMap ID: C01781
Pert ID: BRD-A72703248
Compound Name: SKF-96365
Targets: CYP3A4; TRPC1
MoA: Calcium channel blocker
SMILES: COc1ccc(CCCOC(Cn2ccnc2)c2ccc(OC)cc2)cc1
InchiKey: HLMBXBGDBBCYII-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5410 BRD-A72703248 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5545 BRD-A72703248 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5990 BRD-A72703248 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6392 BRD-A72703248 VCAP 10 uM 24 h 0.24 0.98 0.09 -0.23 -0.77 0.08
44491 BRD-A72703248 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44785 BRD-A72703248 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45105 BRD-A72703248 HEPG2 10 uM 6 h 0.22 0.9 0.02 0.28 0.98 0.36
45905 BRD-A72703248 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46221 BRD-A72703248 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46536 BRD-A72703248 SKB 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
96979 BRD-A72703248 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97058 BRD-A72703248 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
97802 BRD-A72703248 MCF??7.00 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
100312 BRD-A72703248 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).