CMap Candidate Details

Structure:
CMap ID: C01787
Pert ID: BRD-A72988804
Compound Name: tiaprofenic-acid
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CC(C(O)=O)c1ccc(s1)C(=O)c1ccccc1
InchiKey: GUHPRPJDBZHYCJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6688 BRD-A72988804 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7111 BRD-A72988804 A549 10 uM 6 h 0.25 1.06 0.19 0.0 0.0 0.0
7412 BRD-A72988804 HA1E 10 uM 6 h 0.2 0.82 0.0 0.2 0.72 0.02
7803 BRD-A72988804 HT29 10 uM 24 h -0.19 -0.81 0.0 0.24 0.86 0.15
8618 BRD-A72988804 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.24
51684 BRD-A72988804 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.78
51903 BRD-A72988804 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).