CMap Candidate Details

Structure:
CMap ID: C01796
Pert ID: BRD-A73581086
Compound Name: ergometrine
Targets: HTR2A
MoA: Adrenergic receptor agonist; Serotonin receptor agonist
SMILES: CC(CO)NC(=O)C1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34
InchiKey: WVVSZNPYNCNODU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1510 BRD-A73581086 HA1E 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
1844 BRD-A73581086 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
2166 BRD-A73581086 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2650 BRD-A73581086 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41685 BRD-A73581086 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42029 BRD-A73581086 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42233 BRD-A73581086 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42573 BRD-A73581086 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42878 BRD-A73581086 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43269 BRD-A73581086 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.35 1.24 1.24
43431 BRD-A73581086 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43741 BRD-A73581086 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
44026 BRD-A73581086 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).