CMap Candidate Details

Structure:
CMap ID: C17982
Pert ID: BRD-K48735772
Compound Name: PD-158780
Targets: EGFR
MoA: EGFR inhibitor
SMILES: CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1
InchiKey: KFHMLBXBRCITHF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6763 BRD-K48735772 A375 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
7165 BRD-K48735772 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7452 BRD-K48735772 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7669 BRD-K48735772 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.42
7875 BRD-K48735772 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8191 BRD-K48735772 MCF??7.00 10 uM 6 h -0.22 -0.91 0.05 0.29 1.02 0.47
8377 BRD-K48735772 PC3 10 uM 24 h -0.28 -1.15 0.44 0.25 0.9 0.22
8822 BRD-K48735772 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90883 BRD-K48735772 MCF10A 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99595 BRD-K48735772 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).