CMap Candidate Details

Structure:
CMap ID: C00180
Pert ID: BRD-A07000685
Compound Name: hydrocortisone-hemisuccinate
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C1CC[C@]2(O)C(=O)COC(=O)CCC(O)=O
InchiKey: VWQWXZAWFPZJDA-PILPDLGISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6823 BRD-A07000685 A375 10 uM 6 h -0.27 -1.12 0.39 0.0 0.0 0.0
7049 BRD-A07000685 A549 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
7202 BRD-A07000685 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7499 BRD-A07000685 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7931 BRD-A07000685 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8036 BRD-A07000685 MCF??7.00 10 uM 24 h 0.25 1.05 0.18 0.0 0.0 0.0
8289 BRD-A07000685 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8744 BRD-A07000685 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).