CMap Candidate Details

Structure:
CMap ID: C01804
Pert ID: BRD-A73741725
Compound Name: exemestane
Targets: CYP19A1
MoA: Aromatase inhibitor
SMILES: C[C@]12CCC3C(CC(=C)C4=CC(=O)C=C[C@]34C)C1CCC2=O
InchiKey: BFYIZQONLCFLEV-VQIOPMHJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5547 BRD-A73741725 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6410 BRD-A73741725 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
37545 BRD-A73741725 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
37849 BRD-A73741725 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38390 BRD-A73741725 NPC 10 uM 24 h 0.33 1.39 1.01 -0.39 -1.32 1.71
38660 BRD-A73741725 PHH 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
38885 BRD-A73741725 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95370 BRD-A73741725 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95440 BRD-A73741725 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
127006 BRD-A73741725 A375 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
127038 BRD-A73741725 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127061 BRD-A73741725 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127085 BRD-A73741725 HELA 10 uM 24 h 0.25 1.03 0.13 0.3 1.07 0.61
127125 BRD-A73741725 HT29 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
127224 BRD-A73741725 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127264 BRD-A73741725 THP1 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
127303 BRD-A73741725 YAPC 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
135026 BRD-A73741725 A549 0.74 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
135158 BRD-A73741725 JURKAT 0.03 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
135195 BRD-A73741725 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
135243 BRD-A73741725 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).