CMap Candidate Details

Structure:
CMap ID: C18043
Pert ID: BRD-K48923948
Compound Name: BMS-641988
Targets: AR
MoA: Androgen receptor antagonist
SMILES: CCS(=O)(=O)N[C@@H]1C[C@@]2(C)O[C@]1(C)[C@H]1[C@@H]2C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
InchiKey: HYNANJUKEMCYEQ-HIGHGGLBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8945 BRD-K48923948 A375 12 uM 24 h -0.17 -0.71 0.0 -0.27 -0.92 0.34
9207 BRD-K48923948 A549 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9922 BRD-K48923948 HA1E 12 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
10172 BRD-K48923948 HCC515 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10792 BRD-K48923948 HEPG2 12 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.53
11082 BRD-K48923948 HT29 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11178 BRD-K48923948 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11497 BRD-K48923948 NCIH2073 12 uM 6 h 0.0 0.0 0.0 -0.42 -1.42 2.34
12324 BRD-K48923948 NOMO1 12 uM 6 h -0.26 -1.09 0.33 0.0 0.0 0.0
12494 BRD-K48923948 PC3 12 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
13012 BRD-K48923948 THP1 12 uM 6 h 0.0 0.0 0.0 0.2 0.71 0.02
13282 BRD-K48923948 U937 12 uM 6 h 0.22 0.92 0.04 0.21 0.73 0.03
13627 BRD-K48923948 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).