CMap Candidate Details

Structure:
CMap ID: C18048
Pert ID: BRD-K48935217
Compound Name: epothilone
Targets: TUBB
MoA: Microtubule inhibitor
SMILES: C[C@H]1CCC[C@@]2(C)O[C@H]2C[C@H](OC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@H]1O)C(C)=Cc1csc(C)n1
InchiKey: QXRSDHAAWVKZLJ-PVYNADRNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25753 BRD-K48935217 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26376 BRD-K48935217 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26707 BRD-K48935217 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27010 BRD-K48935217 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27319 BRD-K48935217 HT29 10 uM 6 h 0.25 1.03 0.14 0.0 0.0 0.0
27561 BRD-K48935217 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27950 BRD-K48935217 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28264 BRD-K48935217 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28489 BRD-K48935217 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28895 BRD-K48935217 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29227 BRD-K48935217 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29494 BRD-K48935217 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96150 BRD-K48935217 A549 10 uM 24 h -0.25 -1.06 0.25 -0.32 -1.07 0.75
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).