CMap Candidate Details

Structure:
CMap ID: C18062
Pert ID: BRD-K49010888
Compound Name: BRD-K49010888
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(cc2)c3ccccc3)Oc4ccc(NC(=O)CCCCCC(=O)Nc5ccccc5N)cc4CC1=O
InchiKey: VYCOOHAMPRTWAW-YHPNNPEYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
46989 BRD-K49010888 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47281 BRD-K49010888 A549 10 uM 24 h -0.26 -1.09 0.33 0.0 0.0 0.0
47651 BRD-K49010888 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47973 BRD-K49010888 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48296 BRD-K49010888 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48629 BRD-K49010888 HT29 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
49019 BRD-K49010888 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49333 BRD-K49010888 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49514 BRD-K49010888 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90728 BRD-K49010888 NOMO1 3.33 uM 24 h -0.23 -0.96 0.1 -0.4 -1.36 2.02
90740 BRD-K49010888 THP1 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).