CMap Candidate Details

Structure:
CMap ID: C18065
Pert ID: BRD-K49027941
Compound Name: PSB-1115
Targets: ADORA1; ADORA2B
MoA: Adenosine receptor antagonist
SMILES: CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O
InchiKey: UYDRRQPGDSIMNU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6764 BRD-K49027941 A375 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.86
7004 BRD-K49027941 A549 10 uM 24 h -0.21 -0.87 0.02 0.2 0.7 0.02
7331 BRD-K49027941 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7670 BRD-K49027941 HCC515 10 uM 6 h 0.24 1.02 0.13 -0.32 -1.07 0.76
8006 BRD-K49027941 HT29 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
8101 BRD-K49027941 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8378 BRD-K49027941 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8690 BRD-K49027941 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99597 BRD-K49027941 U2OS 10 uM 6 h -0.2 -0.82 0.0 0.28 0.98 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).