CMap Candidate Details

Structure:
CMap ID: C18076
Pert ID: BRD-K49055432
Compound Name: A-66
Targets: --
MoA: --
SMILES: Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1csc(n1)C(C)(C)C
InchiKey: HBPXWEPKNBHKAX-NSHDSACASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92952 BRD-K49055432 ASC 0.04 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.39
92974 BRD-K49055432 CD34 10 uM 24 h -0.3 -1.24 0.64 0.0 0.0 0.0
93031 BRD-K49055432 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93067 BRD-K49055432 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
93114 BRD-K49055432 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93201 BRD-K49055432 HUVEC 10 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
93257 BRD-K49055432 JURKAT 0.12 uM 24 h -0.27 -1.11 0.36 -0.35 -1.19 1.15
93304 BRD-K49055432 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
93344 BRD-K49055432 MDAMB231 0.37 uM 24 h 0.31 1.3 0.72 0.0 0.0 0.0
93410 BRD-K49055432 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93471 BRD-K49055432 SKL 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93530 BRD-K49055432 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93570 BRD-K49055432 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117006 BRD-K49055432 A375 3.33 uM 24 h -0.26 -1.09 0.33 -0.32 -1.09 0.84
117043 BRD-K49055432 A549 0.37 uM 24 h 0.2 0.85 0.0 0.27 0.95 0.31
117121 BRD-K49055432 HCC515 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
117172 BRD-K49055432 HEPG2 0.125 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
117217 BRD-K49055432 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
117257 BRD-K49055432 MCF??7.00 0.04 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
117294 BRD-K49055432 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).