CMap Candidate Details

Structure:
CMap ID: C00181
Pert ID: BRD-A07029265
Compound Name: ipratropium
Targets: CHRM3; CHRM4; CHRM1; CHRM2
MoA: Acetylcholine receptor antagonist
SMILES: CC(C)[N+]1(C)C2CC[C@@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3
InchiKey: OEXHQOGQTVQTAT-RHRUOIOWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1475 BRD-A07029265 HA1E 10 uM 24 h 0.25 1.02 0.13 0.0 0.0 0.0
2026 BRD-A07029265 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2313 BRD-A07029265 PC3 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
2671 BRD-A07029265 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.33 1.71
41640 BRD-A07029265 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42824 BRD-A07029265 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43106 BRD-A07029265 MCF??7.00 10 uM 24 h -0.25 -1.04 0.22 -0.37 -1.25 1.35
43371 BRD-A07029265 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).