CMap Candidate Details

Structure:
CMap ID: C18123
Pert ID: BRD-K49215523
Compound Name: GSK-2636771
Targets: --
MoA: --
SMILES: Cc1nc2c(cc(cc2n1Cc1cccc(c1C)C(F)(F)F)N1CCOCC1)C(O)=O
InchiKey: XTKLTGBKIDQGQL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125261 BRD-K49215523 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125283 BRD-K49215523 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
125323 BRD-K49215523 HEK293 0.125 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
125404 BRD-K49215523 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125452 BRD-K49215523 MCF??7.00 3.33 uM 24 h -0.32 -1.32 0.83 0.0 0.0 0.0
133345 BRD-K49215523 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133429 BRD-K49215523 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133459 BRD-K49215523 HT29 0.03 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.44
133524 BRD-K49215523 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133561 BRD-K49215523 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
133586 BRD-K49215523 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133608 BRD-K49215523 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133638 BRD-K49215523 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).