CMap Candidate Details

Structure:
CMap ID: C18139
Pert ID: BRD-K49294207
Compound Name: BIBU-1361
Targets: EGFR
MoA: EGFR inhibitor
SMILES: CCN(CC)CC1CCN(CC1)c1ncc2ncnc(Nc3ccc(F)c(Cl)c3)c2n1
InchiKey: JUGSLZCFNSTKBN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6887 BRD-K49294207 A375 10 uM 6 h -0.27 -1.14 0.42 0.0 0.0 0.0
7454 BRD-K49294207 HA1E 10 uM 6 h 0.26 1.06 0.19 0.0 0.0 0.0
7672 BRD-K49294207 HCC515 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.77
7878 BRD-K49294207 HT29 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
8193 BRD-K49294207 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8379 BRD-K49294207 PC3 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
8691 BRD-K49294207 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96151 BRD-K49294207 A549 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.52
99602 BRD-K49294207 U2OS 10 uM 6 h 0.16 0.67 0.0 0.27 0.95 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).