CMap Candidate Details

Structure:
CMap ID: C01816
Pert ID: BRD-A74269027
Compound Name: isoxsuprine
Targets: ADRB2
MoA: Adrenergic receptor agonist
SMILES: CC(COc1ccccc1)NC(C)C(O)c2ccc(O)cc2
InchiKey: BMUKKTUHUDJSNZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1708 BRD-A74269027 HA1E 10 uM 6 h -0.27 -1.11 0.36 -0.27 -0.91 0.3
1845 BRD-A74269027 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2697 BRD-A74269027 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41686 BRD-A74269027 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42031 BRD-A74269027 A549 10 uM 6 h -0.21 -0.89 0.04 0.24 0.83 0.12
42234 BRD-A74269027 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
42575 BRD-A74269027 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42880 BRD-A74269027 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.22
43433 BRD-A74269027 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43743 BRD-A74269027 PHH 10 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
44027 BRD-A74269027 SKB 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.26
51353 BRD-A74269027 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51409 BRD-A74269027 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
100317 BRD-A74269027 U2OS 6.66 uM 6 h 0.14 0.6 0.0 0.27 0.96 0.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).