CMap Candidate Details

Structure:
CMap ID: C18174
Pert ID: BRD-K49404994
Compound Name: levetiracetam
Targets: CACNA1B; SV2A
MoA: Calcium channel blocker
SMILES: CC[C@H](N1CCCC1=O)C(N)=O
InchiKey: HPHUVLMMVZITSG-LURJTMIESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25379 BRD-K49404994 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91117 BRD-K49404994 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
125599 BRD-K49404994 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125662 BRD-K49404994 HEK293 0.04 uM 24 h -0.29 -1.21 0.59 -0.42 -1.41 2.02
125757 BRD-K49404994 HUVEC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125955 BRD-K49404994 YAPC 3.33 uM 24 h 0.21 0.86 0.01 0.26 0.94 0.28
133677 BRD-K49404994 A549 0.03 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
133716 BRD-K49404994 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133778 BRD-K49404994 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133811 BRD-K49404994 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
133836 BRD-K49404994 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133871 BRD-K49404994 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133895 BRD-K49404994 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133929 BRD-K49404994 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
133958 BRD-K49404994 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
133991 BRD-K49404994 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).