CMap Candidate Details

Structure:
CMap ID: C01818
Pert ID: BRD-A74391928
Compound Name: ibutilide
Targets: KCNH2; CACNA1C
MoA: Potassium channel blocker
SMILES: CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1
InchiKey: ALOBUEHUHMBRLE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127356 BRD-A74391928 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127429 BRD-A74391928 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127520 BRD-A74391928 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127611 BRD-A74391928 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127648 BRD-A74391928 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127690 BRD-A74391928 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
135346 BRD-A74391928 A549 0.25 uM 24 h -0.25 -1.05 0.23 0.27 0.97 0.35
135371 BRD-A74391928 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135407 BRD-A74391928 HT29 2.22 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
135441 BRD-A74391928 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135473 BRD-A74391928 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).