CMap Candidate Details

Structure:
CMap ID: C18186
Pert ID: BRD-K49448285
Compound Name: BRD-K49448285
Targets: --
MoA: --
SMILES: O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45
InchiKey: GBEDQEGRSFONFW-SIJTWYJSSA-N
Compound Aliases: bisindolylmaleimide

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7167 BRD-K49448285 A549 10 uM 6 h 0.0 0.0 0.0 -0.46 -1.55 15.35
7333 BRD-K49448285 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7673 BRD-K49448285 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.47 -1.59 15.65
7879 BRD-K49448285 HT29 10 uM 24 h 0.28 1.16 0.34 -0.41 -1.38 2.02
8138 BRD-K49448285 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
8516 BRD-K49448285 PC3 10 uM 6 h 0.25 1.03 0.14 0.0 0.0 0.0
8824 BRD-K49448285 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
97269 BRD-K49448285 HAP1 3.33 uM 24 h -0.31 -1.27 0.74 0.0 0.0 0.0
97338 BRD-K49448285 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
99603 BRD-K49448285 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).