CMap Candidate Details

Structure:
CMap ID: C18194
Pert ID: BRD-K49468759
Compound Name: KIN001-266
Targets: --
MoA: --
SMILES: CCN1CCC(CC1)n1cc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)nn1
InchiKey: PHNZIIMWDVXPGG-UHFFFAOYSA-N
Compound Aliases: KIN-001-266

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91808 BRD-K49468759 HS578T 2.22 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91879 BRD-K49468759 MCF??7.00 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91937 BRD-K49468759 SKBR3 0.08 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.13
92869 BRD-K49468759 A375 10 uM 24 h -0.22 -0.92 0.06 0.35 1.23 1.19
92896 BRD-K49468759 A549 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.11
92933 BRD-K49468759 ASC 0.04 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
92996 BRD-K49468759 CD34 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
93042 BRD-K49468759 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93084 BRD-K49468759 HEK293 1.11 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
93127 BRD-K49468759 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93172 BRD-K49468759 HEPG2 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93222 BRD-K49468759 HUVEC 10 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
93277 BRD-K49468759 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93316 BRD-K49468759 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93358 BRD-K49468759 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93395 BRD-K49468759 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93446 BRD-K49468759 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93486 BRD-K49468759 SKL 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
93544 BRD-K49468759 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93584 BRD-K49468759 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).