CMap Candidate Details

Structure:
CMap ID: C18210
Pert ID: BRD-K49519092
Compound Name: immethridine
Targets: HRH3
MoA: Histamine receptor agonist
SMILES: C(c1cnc[nH]1)c1ccncc1
InchiKey: DFVSGZHJSIEEQQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5211 BRD-K49519092 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
5459 BRD-K49519092 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5783 BRD-K49519092 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6031 BRD-K49519092 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6102 BRD-K49519092 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6197 BRD-K49519092 PC3 10 uM 24 h -0.16 -0.68 0.0 0.0 0.0 0.0
6431 BRD-K49519092 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37393 BRD-K49519092 A549 10 uM 6 h 0.0 0.0 0.0 0.3 1.08 0.64
37679 BRD-K49519092 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
37914 BRD-K49519092 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38503 BRD-K49519092 NPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).