CMap Candidate Details

Structure:
CMap ID: C18211
Pert ID: BRD-K49519144
Compound Name: LY-2140023
Targets: GRM3
MoA: Glutamate receptor agonist
SMILES: N[C@]1(CS(=O)(=O)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
InchiKey: AVDUGNCTZRCAHH-MDASVERJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49850 BRD-K49519144 A375 10 uM 6 h -0.16 -0.65 0.0 0.21 0.76 0.05
50017 BRD-K49519144 A549 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
50193 BRD-K49519144 HA1E 10 uM 6 h 0.26 1.07 0.19 -0.28 -0.95 0.4
50370 BRD-K49519144 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50543 BRD-K49519144 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50671 BRD-K49519144 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50931 BRD-K49519144 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51036 BRD-K49519144 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136435 BRD-K49519144 SHSY5Y 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).