CMap Candidate Details

Structure:
CMap ID: C18229
Pert ID: BRD-K49577446
Compound Name: flunisolide
Targets: NR3C1
MoA: Cytochrome P450 inhibitor
SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
InchiKey: XSFJVAJPIHIPKU-QYOXGAPUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3034 BRD-K49577446 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3216 BRD-K49577446 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
19059 BRD-K49577446 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20365 BRD-K49577446 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20913 BRD-K49577446 MCF??7.00 10 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
21440 BRD-K49577446 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21758 BRD-K49577446 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.22
41940 BRD-K49577446 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42375 BRD-K49577446 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.43
42999 BRD-K49577446 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43563 BRD-K49577446 NPC 10 uM 24 h -0.27 -1.13 0.41 -0.39 -1.31 1.71
43863 BRD-K49577446 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44125 BRD-K49577446 SKB 10 uM 24 h -0.25 -1.04 0.22 0.22 0.77 0.06
99605 BRD-K49577446 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).