CMap Candidate Details

Structure:
CMap ID: C18266
Pert ID: BRD-K49687221
Compound Name: BRD-K49687221
Targets: --
MoA: --
SMILES: C[C@@H](CO)N1C[C@H](C)[C@H](CN(C)C(=O)Nc2ccc(F)cc2)Oc3ccc(NC(=O)C4CC4)cc3C1=O
InchiKey: OTRZZVMKCVISTM-UAVUOLJFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
54314 BRD-K49687221 VCAP 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
63529 BRD-K49687221 MCF??7.00 4 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
81354 BRD-K49687221 A375 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
81523 BRD-K49687221 A549 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
81696 BRD-K49687221 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
82296 BRD-K49687221 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
82541 BRD-K49687221 PC3 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).