CMap Candidate Details

Structure:
CMap ID: C01828
Pert ID: BRD-A74907996
Compound Name: equol
Targets: ESR1; ESR2
MoA: Estrogen receptor agonist
SMILES: Oc1ccc(cc1)C2COc3cc(O)ccc3C2
InchiKey: ADFCQWZHKCXPAJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
119169 BRD-A74907996 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119200 BRD-A74907996 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119226 BRD-A74907996 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
119255 BRD-A74907996 HCC515 0.37 uM 24 h 0.29 1.2 0.43 0.23 0.82 0.1
119286 BRD-A74907996 HEPG2 10 uM 24 h -0.21 -0.87 0.02 -0.33 -1.11 0.92
119314 BRD-A74907996 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119340 BRD-A74907996 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
119364 BRD-A74907996 PC3 0.37 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).