CMap Candidate Details

Structure:
CMap ID: C01830
Pert ID: BRD-A74975734
Compound Name: homatropine
Targets: CHRM1
MoA: Acetylcholine receptor antagonist
SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)c3ccccc3
InchiKey: ZTVIKZXZYLEVOL-MCOXGKPRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6690 BRD-A74975734 A375 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
7112 BRD-A74975734 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7262 BRD-A74975734 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7805 BRD-A74975734 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8244 BRD-A74975734 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.42 2.02
8470 BRD-A74975734 PC3 10 uM 6 h -0.19 -0.81 0.0 0.0 0.0 0.0
8620 BRD-A74975734 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).