CMap Candidate Details

Structure:
CMap ID: C01831
Pert ID: BRD-A74980173
Compound Name: gatifloxacin
Targets: --
MoA: --
SMILES: COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1
InchiKey: XUBOMFCQGDBHNK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1367 BRD-A74980173 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
19219 BRD-A74980173 A549 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
20210 BRD-A74980173 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20841 BRD-A74980173 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21686 BRD-A74980173 VCAP 10 uM 6 h 0.22 0.93 0.04 0.0 0.0 0.0
91394 BRD-A74980173 HUH7 8 uM 72 h 0.34 1.42 1.1 0.0 0.0 0.0
126353 BRD-A74980173 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126414 BRD-A74980173 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
126464 BRD-A74980173 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126546 BRD-A74980173 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134386 BRD-A74980173 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
134446 BRD-A74980173 HT29 0.25 uM 24 h 0.33 1.36 0.97 0.0 0.0 0.0
134481 BRD-A74980173 HUVEC 0.03 uM 24 h -0.29 -1.19 0.55 -0.35 -1.19 1.15
134531 BRD-A74980173 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134614 BRD-A74980173 PC3 0.08 uM 24 h -0.21 -0.89 0.04 0.26 0.91 0.23
134642 BRD-A74980173 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).