CMap Candidate Details

Structure:
CMap ID: C18320
Pert ID: BRD-K49890030
Compound Name: gavestinel
Targets: --
MoA: --
SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1C=CC(=O)Nc3ccccc3
InchiKey: WZBNEZWCNKUOSM-VOTSOKGWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2890 BRD-K49890030 HA1E 10 uM 24 h 0.19 0.79 0.0 -0.28 -0.96 0.43
3219 BRD-K49890030 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3517 BRD-K49890030 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3817 BRD-K49890030 VCAP 10 uM 24 h 0.23 0.98 0.09 0.32 1.13 0.8
41777 BRD-K49890030 A375 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
42100 BRD-K49890030 A549 10 uM 6 h 0.16 0.67 0.0 0.0 0.0 0.0
42376 BRD-K49890030 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42697 BRD-K49890030 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43000 BRD-K49890030 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43323 BRD-K49890030 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43564 BRD-K49890030 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
43864 BRD-K49890030 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
99609 BRD-K49890030 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).