CMap Candidate Details

Structure:
CMap ID: C18340
Pert ID: BRD-K49945136
Compound Name: GR-113808
Targets: HTR4
MoA: Serotonin receptor antagonist
SMILES: Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12
InchiKey: MOZPSIXKYJUTKI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5212 BRD-K49945136 A375 10 uM 6 h -0.17 -0.7 0.0 0.38 1.34 1.72
5460 BRD-K49945136 HA1E 10 uM 6 h 0.0 0.0 0.0 0.35 1.23 1.19
5784 BRD-K49945136 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6032 BRD-K49945136 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6103 BRD-K49945136 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6198 BRD-K49945136 PC3 10 uM 24 h 0.0 0.0 0.0 0.37 1.29 1.49
6562 BRD-K49945136 VCAP 10 uM 6 h -0.3 -1.26 0.71 0.27 0.97 0.34
37293 BRD-K49945136 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37680 BRD-K49945136 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37915 BRD-K49945136 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38504 BRD-K49945136 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
38738 BRD-K49945136 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).